Information Systems Development Success: Perspective of Software Development Team Members

The traditional models of IS success measure success from the viewpoint of the system, users, and the organization. The system viewpoint is measured by information quality, system quality, and service quality; the users’ viewpoint by user satisfaction, use, and individual net benefits; and the organization’s viewpoint by organizational net benefits. This study adds the development team’s viewpoint. I decompose system quality into its functional and nonfunctional components and combine them with new constructs to create Information System Development (ISD) success. Like IS Success, ISD Success is a comprehensive model composed of multiple interrelated dimensions: practitioner satisfaction, project manager satisfaction, and the antecedents to these constructs, which include functional system quality, non-functional system quality, and process quality. Unlike the traditional models of IS success, ISD Success can be used to evaluate systems during the development cycle as well as on projects that never reach completion or are never used

Toward a Model of Information System Development Success: Perceptions of Information Systems Development Team Members

Many information systems development (ISD) projects are deemed a failure in the field. However, several practitioners and researchers argue these projects could actually be considered successful if we used a broader definition of software development project success. Answering the call for further research on what makes ISD projects successful, this paper describes the process used to build the model of ISD Success, which includes a thorough literature review to create an initial model followed by semi-structured interviews conducted to validate the model and to allow for the discovery of emergent constructs, sub-constructs, and hypotheses. The model is tested with data collected from practitioners using Partial Least Squares (PLS) analysis. The paper concludes with a discussion of the findings and conclusions

Nucleic Acid Amplification Tests for Diagnosis of Smear-Negative TB in a High HIV-Prevalence Setting: A Prospective Cohort Study

Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. Few studies have evaluated the clinical impact of these tests in low-income countries with high burdens of TB and HIV.We prospectively enrolled 211 consecutive adults with cough ≥2 weeks and negative sputum smears at Mulago Hospital in Kampala, Uganda. We tested a single early-morning sputum specimen for Mycobacterium tuberculosis DNA using two nucleic acid amplification tests: a novel in-house polymerase chain reaction targeting the mycobacterial secA1 gene, and the commercial Amplified® Mycobacterium tuberculosis Direct (MTD) test (Gen-Probe Inc, San Diego, CA). We calculated the diagnostic accuracy of these index tests in reference to a primary microbiologic gold standard (positive mycobacterial culture of sputum or bronchoalveolar lavage fluid), and measured their likely clinical impact on additional tuberculosis cases detected among those not prescribed initial TB treatment.Of 211 patients enrolled, 170 (81%) were HIV-seropositive, with median CD4+ T-cell count 78 cells/µL (interquartile range 29-203). Among HIV-seropositive patients, 94 (55%) reported taking co-trimoxazole prophylaxis and 29 (17%) reported taking antiretroviral therapy. Seventy-five patients (36%) had culture-confirmed TB. Sensitivity of MTD was 39% (95% CI 28-51) and that of secA1 was 24% (95% CI 15-35). Both tests had specificities of 95% (95% CI 90-98). The MTD test correctly identified 18 (24%) TB patients not treated at discharge and led to a 72% relative increase in the smear-negative case detection rate.The secA1 and MTD nucleic acid amplification tests had moderate sensitivity and high specificity for TB in a predominantly HIV-seropositive population with negative sputum smears. Although newer, more sensitive nucleic acid assays may enhance detection of Mycobacterium tuberculosis in sputum, even currently available tests can provide substantial clinical impact in smear-negative populations